They’re still in the early days. The thinkpad x60 writeup, for example, walks through reviving some network drivers.

In my experience though the declarative build system acts as a ratchet. No golden bash history so you recall all the steps. Basically no “works on my machine”. The community is pretty great too. I’d recommend giving it a look. The Linux-Libre kernel may also be a good fit for your needs (default for Guix).

I use Guix with the latest Linux kernel via nonguix and love it. The GNU Hurd kernel is always there though!