until now I had organized my papers into a large pile, and finding any paper was a horizontal nightmare. Now they are all hole punched and in a binder… because i staple in the top left of the paper, i hole punch on the right side; so that i can quickly browse the papers in the binder (staple out).
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Absolute peak content for this community.
Is it just me or are all the documents upside down in the binder?
E.g.
Upside down and back to front; because when I print papers I staple them in the top left for reading
I wanted the stapled papers to be browsable in the binder, so I bound them on the other side, so I can grab by the sapler corner and turn the entire paper
Gigabrain strats here
Am I reading this correctly — the hypothesis is that bipolar mania is downstream of how bipolar people metabolize sugars? Like when you give kids too much sugar and they’re hyperactive (allegedly)? That’s bananas!
https://doi.org/10.1038/s41380-024-02431-w
Am I reading this correctly — the hypothesis is that bipolar mania is downstream of how bipolar people metabolize sugars? Like when you give kids too much sugar and they’re hyperactive (allegedly)? That’s bananas!
kinda - after a long enough time of sugar overload the brain insulin ratio gets skewed and there is a brain energy crisis that may be the underlying etiology of various brain issues including bipolar (and maybe hyperactivity).
I know I should read the paper because you linked it… But I’m curious about that as a hypothesis because I would have presumed that people with poorly controlled diabetes with a higher HbA1c would the have higher rates of brain issues ? Aside from the vascular cognitive impairment it’s nothing I’ve noticed anecdotally
It’s a hypothesis paper framing the guidelines for future research.
Yes, poorly controlled t2d is at greater risk for NDDs as far as I’m aware.
https://pmc.ncbi.nlm.nih.gov/articles/PMC7358107/ - Eleven-year multimorbidity burden among 637 255 people with and without type 2 diabetes: a population-based study using primary care and linked hospitalisation data
I have not read this paper, but it has a graph that is illustrative
comorbidity graph
odds ratios tree
Sure, the astronauts had “Tang”, but they didn’t have “Duotang”!
I almost never print off a paper anymore. I do pay $20 per year for Zotero cloud storage however.
You know what? That’s great! I actualy love to organize my paperwork in binders. It always feels like a chore to get started, but by the time I am done, I feel satisfied and I actually kinda had fun doing it.
